ea0047oc47 | Innovative Theranostics | Theranostics2016
Bandara Nilantha
, Hathi Deep
, Akers Walter J
, Laforest Richard
, Shoghi Kooresh I
, Rogers Buck E
, Shokeen Monica
Multiple myeloma (MM) is a B-cell tumor of monoclonal plasma cells in the bone marrow and is the second most common age-related hematologic malignancy reported in the United States. Very late antigen-4 (VLA-4, α4β1 integrin, CD49d/CD29) is overexpressed on MM. LLP2A is a highly specific peptidomimetic ligand that targets activated VLA-4 with high affinity. In this study, we evaluated 68Ga radiolabeled-DOTA-PEG4-LLP2A tracer...